Unconventional Gold-Catalyzed One-Pot/Multicomponent Synthesis of Propargylamines Starting from Benzyl Alcohols
نویسندگان
چکیده
A formal homogeneous gold-catalyzed A3-coupling, starting from benzyl alcohols, is reported for the straightforward synthesis of propargylamines. This first process where these highly valuable compounds have been synthesized, corresponding alcohols in a one-pot oxidation procedure using MnO2, followed by HAuCl4·3H2O catalyzed multicomponent reaction. The final products are obtained with very good yields short reaction times, which fundamental interest pharmaceuticals. usefulness and efficiency our methodology successfully compared against same aldehydes.
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ژورنال
عنوان ژورنال: Catalysts
سال: 2021
ISSN: ['2073-4344']
DOI: https://doi.org/10.3390/catal11040513